Optimizing Treatment
Considerations When Optimizing Regimens
A variety of important factors should be considered in the treatment decision1
Providers may hesitate to change a patient’s regimen, but there may be compelling reasons to do so,
including1:
Reducing pill burden
Tolerability and toxicity considerations
Potential drug-drug
interactions
Food requirements
Patient access
Barrier to resistance
How do you approach real-world discussions for switching treatments?
Having conversations around optimizing regimens can help providers and patients who are assessing their options.
Wide Diversity in Clinical Trial Data May Help Inform Treatment Discussions
Increasing the amount of clinical trial data available for specific populations may enhance patient trust2
Increasing diversity and inclusion in clinical trials can provide more generalizable evidence—potentially improving patient trust and advancing health equity. Enhanced patient trust can lead to better retention in care, especially when patients are included as partners.2
While every patient is different, people living with HIV may be inclined towards taking a collaborative approach to shared clinical decision-making.
IN A 2010 STUDY, 7 OUT OF 10
patients preferred to engage in shared decision-making when it came to their HIV treatment (n=434)3
Please see full Prescribing Information for BIKTARVY® and DESCOVY®, including BOXED WARNINGS.
References:
- Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. Department of Health and Human Services. Updated September 12, 2024. Accessed September 24, 2024. https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf
- Corneli A, Hanlen-Rosado E, McKenna K, et al. Enhancing diversity and inclusion in clinical trials. Clin Pharmacol Ther. 2023;113(3):489-499.
- Kumar R, Korthuis PT, Saha S, et al. Decision-making role preferences among patients with HIV: associations with patient and provider characteristics and communication behaviors. J Gen Intern Med. 2010;25(6):517-523.